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Manufacturing costs for peptides scale approximately linearly with dose, particularly for synthetic peptides and recombinant proteins produced at commercial scale

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However, some non-peptide GLP-1 agonists are currently being studied in clinical trials, but none are FDA-approved yet

Although the FAERS database aids in detecting rare adverse events via spontaneous reporting, its propensity to overestimate unexpected adverse events linked to new therapies makes it inappropriate for comparative analysis of adverse event frequencies among pharmaceuticals